Liraglutide-Induced Autoimmune Hepatitis

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Liraglutide-induced autoimmune hepatitis.

IMPORTANCE Use of incretin-based hypoglycemic agents is increasing, but safety data remain limited. We treated a woman with marker-negative autoimmune hepatitis associated with the glucagon-like peptide 1 agonist liraglutide. OBSERVATIONS A young woman with type 2 diabetes mellitus and vitiligo presented with a 10-day history of acute hepatitis. Other than starting liraglutide therapy 4 month...

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Autoimmune hepatitis

Autoimmune hepatitis is (AIH) is a chronic hepatitis that occurs in children and adults of all ages. It is characterized by immunologic and autoimmune features, including circulating auto antibodies and high serum globulin concentrations. It was first described in the 1950s by term of chronic active hepatitis. It has 2 types with different auto antibodies. Diagnosis is based upon serologic and ...

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Drug induced liver injury (DILI) is a disease caused by xenobiotics (drugs, herbal or diet products) and diagnosed by exclusion of other causes. Some drugs that cause DILI can also cause drug induced autoimmune hepatitis (DI-AIH) by triggering the immune response against liver proteins (1, 2). A 24-yr old male patient in 2015, was admitted to Turkiye Yuksek Ihtisas Hospital, gastroenterology cl...

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Atovaquone/proguanil‐induced autoimmune‐like hepatitis

We report a novel association between the commonly used antimalarial medication atovaquone/proguanil and drug-induced autoimmune-like hepatitis. The patient developed severe liver disease fulfilling biochemical, immunologic, and histologic criteria for the diagnosis of autoimmune hepatitis after the inadvertent rechallenge with the offending drug, which had caused self-limited hepatitic symptom...

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Autoimmune hepatitis induced by the prolonged hepatitis A virus infection.

Hepatitis A virus (HAV) is the most common cause of acute viral hepatitis in the world. Rarely, acute infection may persist for a long time. Autoimmune hepatitis (AIH) may provide anti-HAV IgM positivity detection for a prolonged time. On the other hand, HAV as an infectious agent may also trigger AIH. Here we presented a case which seemed like a simple acute viral hepatitis A infection at the ...

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ژورنال

عنوان ژورنال: JAMA Internal Medicine

سال: 2014

ISSN: 2168-6106

DOI: 10.1001/jamainternmed.2014.674